Semax
Semax is a powerful neuropeptide that enhances brain function, sharpens mental clarity, and protects the nervous system from damage. Originally developed in Russia for stroke recovery, it has since become one of the most sought-after cognitive enhancement peptides in the world. It works by rapidly boosting levels of BDNF and NGF — the brain's own growth factors responsible for building and maintaining neurons — while simultaneously reducing inflammation in the brain and improving blood flow to critical cognitive centers.
Key Benefits
- Dramatically improves focus, memory, and mental processing speed
- Elevates mood and reduces anxiety without sedation
- Accelerates learning and information retention
- Protects brain cells from oxidative stress and neuroinflammation
- Supports recovery from brain injury, stroke, and cognitive decline
- Increases BDNF levels — the primary driver of neuroplasticity
- Fast-acting with effects felt within hours of administration
- Non-addictive with no withdrawal effects
Semax is the go-to peptide for anyone looking to optimize cognitive performance, recover from neurological setbacks, or protect long-term brain health. ≥99% purity, third-party HPLC verified.
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Molecular Weight | 813.93 g/mol |
| Molecular Formula | C37H51N9O10S |
| CAS Number | 80714-61-4 |
| Target / Receptor | BDNF/trkB pathway; ACTH fragment analog |
| Physical Form | Lyophilized Powder |
| Storage | -20°C, protect from light |
Reconstitution Guide
For laboratory research use only. Follow aseptic technique throughout.
Equilibrate Temperature
Remove the vial from the freezer and allow it to reach room temperature before opening. This prevents condensation from entering the vial.
Wait 15–20 minutes at room temperature
Add Bacteriostatic Water
Reconstitute in sterile saline or bacteriostatic water. Stable for up to 3 weeks at 4°C after reconstitution.
Use a sterile 1 mL insulin syringe for precision
Dissolve Gently
Gently swirl or roll the vial between your palms until the peptide is fully dissolved. Do not shake vigorously or vortex — this can cause aggregation and degrade the compound.
Solution should appear clear to slightly opalescent
Aliquot & Store
Transfer reconstituted solution into sterile single-use vials to avoid repeated needle punctures. Store working aliquots at 4°C (use within 28 days) or freeze at -20°C for long-term storage.
Avoid more than 3 freeze-thaw cycles
Concentration Reference (per 1 mg peptide)
| Bacteriostatic Water | Concentration | Per mL Dose |
|---|---|---|
| 1 mL | 1 mg/mL | 1,000 mcg/mL |
| 2 mL | 0.5 mg/mL | 500 mcg/mL |
| 5 mL | 0.2 mg/mL | 200 mcg/mL |
| 10 mL | 0.1 mg/mL | 100 mcg/mL |
Storage Conditions
-20°C, protect from light
